you know about this company/organistation?
Research the company or organisation
Many organisations send you additional
information with the application pack. Most organisations now
have a website. Go the there "About us" page and download
relevant information. Particularly the lastest news (you can base
one of your question to them on this) - that will impress them
you've done your homework.
You can also ask your friends
if they know who works there now or in the past. Get in contact
with them and tell you have an interview and like to anything
they can tell you about the organisation/company.
Get to the organisations history
and major events or upheavals coming up. Understand there general
aims and goals. They will be impressed. After they have given
you a brief overview of the company at the beginning, you can
pipe up and say "yes and I understand you are bringing this
new system ..........., on board later this year".